P-N Semiconductor Membranes for Ion Filtering and Rectification
Jean-Pierre Leburton's research at the Beckman Institute deals with transport and optical processes in semiconductor nanostructures such as quantum wires and quantum dots that exhibit a high degree of quantization dependent on the semiconductor materials and geometrical confinement.
Carbon Nanotechnology: Scientific and Technological Issues
Carbon nanotechnologies based on single-walled carbon nanotubes (SWNTs) and graphene (a single atomic layer of graphite) are being pursued for a wide range of technological applications ranging from chemical sensing to post-silicon nanoelectronics.
Using Mass Spectrometry to Understand Membrane Organization
Our ability to engineer tissues and biomimetic devices hinges upon an understanding of the structure-function relationship in healthy and diseased cells. Our laboratory utilizes materials characterization, quantitative engineering principles, cell biology and chemistry to elucidate the influence of molecular organization on cellular function.
Silicon nanomembranes are extremely thin (<10 to 100s of nm), flexible, strain-engineered, single-crystal sheets. Their novelty is several-fold: they are flexible, they are readily transferable to other hosts and conform and bond easily, they are stackable, and they can take on a large range of shapes (tubes, spirals,ribbons, wires) via appropriate strain engineering and patterning.
Ion Selectivity in Synthetic and Natural Channels
Transport across membranes and nanopores can be characterized by static equilibrium properties as well as by nonequilibrium dynamic properties. For example, equilibrium selectivity properties of a nanopore can be characterized by the difference in interaction free energy for transferring one ion from bulk liquid water into a pore compared to another ion.
Controlling Membrane Organization: Effects of pH, Ions, and composition
Our main research interests are in determining, at the molecular level, how cell membranes are organized and how that organization relates to function.
Modeling (Semi) Unstructured Proteins
The past century has seen tremendous progress in determining the biochemical and biophysical processes that constitute life. One exciting consequence of this understanding is the possibility of developing mathematical models of biological function that are accurate and even predictive.
The Functional Protocell concept
We define the “functional protocell" as a nanoporous solid surrounded by a membrane. The cavities in the solid can be filled with any desired electrolyte up to the limit of solubility. The surrounding membrane can contain any combination of membrane proteins. Thus the functional protocell can be imbued with any array of intracellular and membrane processes that are desired.
Spectroscopy and Modeling to Infer Channel Structure and Function
We are particularly interested in issues about ion permeation, ion selectivity, gating, and channel inhibitors. We are currently working on the KcsA channel, the OmpF porin, and the gramicidin A> channel. We are also spending our efforts in the development of new computational approaches for studying biological macromolecular systems.
CAD of MEMS & NEMS: State of the Art & Future Challenges
Computer aided design environments are very mature and used extensively for the design of every integrated electronical component that is commercially available to all of us. This presentation reviews recent developments in taking that framework and making it pertinent to the design of systems that include MEMS and NEMS devices.
Ferroelectric BaTiO3 Nanowires: Synthesis, Properties, and Device Applications
One dimensional ferroelectric nanowires have attracted much attention due to its interests in fundamental physics and potential applications in Nanoelectromechanical Systems (NEMS), non-volatile ferroelectric memories, and sensors. Domain structure is the most important property of ferroelectric materials determining their applications.